homocysteine molecule
HOMOCYSTEINE levels that are too high increase the risk of heart disease, stroke, and dementia.
Homocysteine is an amino acid produced in the body from the metabolism of protein-rich foods that contain the amino acid Methionine. Normally, the body has mechanisms to maintain Homocysteine levels within an appropriate range (not exceeding 10 micromoles/L).
High levels of Homocysteine in the blood increase the risk of damage and inflammation to the arterial walls, leading to the formation of fat deposits that clog and form plaques, blocking blood circulation. This can result in insufficient blood supply to vital organs such as the heart and brain, raising the risk of heart disease, stroke, and dementia.
We can reduce the risk of these diseases by ensuring adequate intake of vitamins B6, B9 (Methyl-Folate), and B12.
HOMOCYSTEINE levels that are too high increase the risk of heart disease, stroke, and dementia.
High levels of Homocysteine can occur due to several reasons, such as abnormalities in the MTHFR gene, which impair the body's ability to convert Homocysteine to Methionine, or insufficient intake of vitamins B6, B9 (5-MTHF), or B12.
Typically, Methionine is converted into Homocysteine after the body uses it to regulate DNA function and the processes of metabolism and energy production in cells. At the same time, Homocysteine can be converted back into Methionine through the cooperation of 5-MTHF and B12.
Some of the Homocysteine can also be converted into the amino acid Cysteine with the help of B6. Cysteine is important for immune system function and helps reduce inflammation in the body.
We need to ensure adequate intake of 5-MTHF, B6, and B12 to effectively convert excess Homocysteine into Methionine and Cysteine, which the body needs.
Problems:
- High level of Homocysteine leads to Cardiovascular diseases e.g. Strokes & Heart attack
- Diabetes
- Dementia & Alzheimer’s disease
- Osteoporosis
- Pregnancy Complications
- Concentration and underachievement
Solution:
- Vitamin B6, B9 (5 MTHF) & B12 work together to maintain the homeostasis (balance) of Homocysteine in the body
Suitable for:
- Those who have methylation gene mutations
- Those who have Homocysteine-related symptoms
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Excess folic acid that your body can't process can lead to Unmetabolized Folic Acid (UMFA), which can negatively impact immune function and nervous system health.
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Recommended Daily Dosage (WHO Guidelines):
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